Temporal trends and space–time distribution of leprosy relapse in Brazil from 2001 to 2021

Author:

Boigny Reagan Nzundu1ORCID,de Sousa Cavalcante Kellyn Kessiene1ORCID,Florencio Caroline Mary Gurgel Dias1ORCID,Nogueira Paula Sacha Frota2ORCID,Gomes Ciro Martins3ORCID,Alencar Carlos Henrique14ORCID

Affiliation:

1. Federal University of Ceará, Faculty of Medicine, Postgraduate Program in Public Health , Prof. Costa Mendes street, 1608th – 5° Floor – Rodolfo Teófilo, Fortaleza, CE 60430-140 , Brazil

2. Federal University of Ceará, Faculty of Pharmacy, Dentistry and Nursing, Department of Nursing , Alexandre Baraúna street, 1115th – Rodolfo Teófilo, Fortaleza, CE 60430-160 , Brazil

3. University of Brasília, Faculty of Medicine, Postgraduate Program in Medical Sciences , Campus Universitário Darcy Ribeiro, Brasília-DF, 70910-900 , Brazil

4. Federal University of Ceará, Faculty of Medicine, Postgraduate Program in Pathology , Alexandre Baraúna street, 949 – Rodolfo Teófilo, Fortaleza, CE 60430-160 , Brazil

Abstract

Abstract Background To analyse the temporal trends and spatiotemporal distribution of leprosy relapse in Brazil from 2001 to 2021. Methods An ecological study with a temporal trend approach and space–time analysis of leprosy relapse in Brazil was carried out with data from the Notifiable Diseases Information System. Results A total of 31 334 patients who experienced leprosy relapse were identified. The number of recurrent cases tended to increase throughout the study period, and this increase was significant among females and in almost all age groups, except for those <15, 50–59 and ≥70 y. Several clusters of high- and low-risk patients were identified across all regions with a heterogeneous distribution. Conclusions The burden of relapse showed an increasing trend in some groups and was distributed in all regions.

Publisher

Oxford University Press (OUP)

Reference52 articles.

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2. Diretrizes para vigilância, atenção e eliminação da Hanseníase como problema de saúde pública: manual técnico-operacional;Brasil. Ministério da Saúde. Secretaria de Vigilância em Saúde. Departamento de Vigilância das Doenças Transmissíveis

3. Guia prático sobre a hanseníase;Ministério da Saúde. Secretaria de Vigilância em Saúde. Departamento de Vigilância das Doenças Transmissíveis

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