Mutations in glycyl-tRNA synthetase impair mitochondrial metabolism in neurons

Author:

Boczonadi Veronika1,Meyer Kathrin2,Gonczarowska-Jorge Humberto34,Griffin Helen1,Roos Andreas13,Bartsakoulia Marina1,Bansagi Boglarka1,Ricci Giulia15,Palinkas Fanni1,Zahedi René P3,Bruni Francesco67,Kaspar Brian28,Lochmüller Hanns1910,Boycott Kym M11,Müller Juliane S1,Horvath Rita1

Affiliation:

1. Wellcome Centre for Mitochondrial Research, Institute of Genetic Medicine, Newcastle University, NE1 3BZ Newcastle upon Tyne, UK

2. The Research Institute, Nationwide Children’s Hospital, Columbus, OH 43205, USA

3. Leibniz-Institute für Analytische Wissenschaften-ISAS-e.V., Dortmund 44139, Germany

4. CAPES Foundation, Ministry of Education of Brazil, Brazil

5. Department of Clinical and Experimental Medicine, University of Pisa, Pisa 56126, Italy

6. Institute of Neuroscience, Wellcome Centre for Mitochondrial Research, Newcastle University, NE2 4HH Newcastle upon Tyne, UK

7. Department of Biosciences, Biotechnologies and Biopharmaceutics, University of Bari Aldo Moro, 70121 Bari, Italy

8. Department of Neuroscience, Molecular, Cellular, and Developmental Biology Graduate Program and Integrated Biomedical Science Graduate Program, College of Medicine, The Ohio State University, Columbus, OH 43210, USA

9. Department of Neuropediatrics and Muscle Disorders, Medical Center – University of Freiburg, Faculty of Medicine, Freiburg 79160, Germany

10. Centro Nacional de Análisis Genómico (CNAG-CRG), Center for Genomic Regulation, Barcelona Institute of Science and Technology (BIST), Barcelona 08028, Spain

11. Department of Genetics, CHEO Research Institute, University of Ottawa, K1H 8L1 Ottawa, Canada

Funder

Medical Research Council

European Research Council

European Union Seventh Framework Programme

Wellcome Trust

Newton Fund

Publisher

Oxford University Press (OUP)

Subject

Genetics(clinical),Genetics,Molecular Biology,General Medicine

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