Variable rescue of microtubule and physiological phenotypes in mdx muscle expressing different miniaturized dystrophins

Author:

Nelson D’anna M1,Lindsay Angus12,Judge Luke M3,Duan Dongsheng4,Chamberlain Jeffrey S3,Lowe Dawn A2,Ervasti James M1

Affiliation:

1. Department of Biochemistry, Molecular Biology and Biophysics, University of Minnesota, Minneapolis, MN 55455, USA

2. Department of Rehabilitation Medicine, University of Minnesota, Minneapolis, MN 55455, USA

3. Department of Neurology, University of Washington, Seattle, WA 98195, USA

4. Department of Molecular Microbiology and Immunology, University of Missouri, Columbia, MO 65212, USA

Funder

National Institute of Arthritis and Musculoskeletal and Skin Diseases

National Institute of Neurological Disorders and Stroke

Publisher

Oxford University Press (OUP)

Subject

Genetics (clinical),Genetics,Molecular Biology,General Medicine

Reference69 articles.

1. Dystrophin: the protein product of the Duchenne muscular dystrophy locus;Hoffman;Cell,1987

2. The molecular basis for Duchenne versus Becker muscular dystrophy: correlation of severity with type of deletion;Koenig;Am. J. Hum. Genet,1989

3. The dystrophin complex forms a mechanically strong link between the sarcolemma and costameric actin;Rybakova;J. Cell Biol,2000

4. Dystrophin is a microtubule-associated protein;Prins;J. Cell Biol,2009

5. Microtubule binding distinguishes dystrophin from utrophin;Belanto;Proc. Natl. Acad. Sci. U. S. A,2014

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