Elevated glucose induction of thrombospondin-1 up-regulates fibronectin synthesis in proximal renal tubular epithelial cells through TGF-β1 dependent and TGF-β1 independent pathways

Author:

Yung Susan,Lee Candice Y. Y.,Zhang Qing,Lau Shuk Kei,Tsang Ryan C. W.,Chan Tak Mao

Publisher

Oxford University Press (OUP)

Subject

Transplantation,Nephrology

Reference20 articles.

1. Chiarelli F, Trotta D, Verrotti A, Mohn A. Kidney involvement and disease in patients with diabetes. Panminerva Med2003; 45: 23–41

2. Nath KA. Tubulointerstitial changes as a major determinant in the progression of renal damage. Am J Kidney Dis1992; 20: 1–17

3. Phillips AO, Steadman R, Morrisey K, Williams JD. Polarity of stimulation and secretion of transforming growth factor beta 1 by cultured proximal tubular cells. Am J Pathol1997; 150: 1101–1111

4. Phillips AO, Topley N, Steadman R, Morrisey K, Williams JD. Induction of TGF-beta1 synthesis in D-glucose primed human proximal tubular cells by IL-1beta and TNF alpha. Kidney Int1996; 50: 1546–1554

5. Lee HB, Yu MR, Yang Y, Jiang Z, Ha H. Reactive oxygen species-regulated signaling pathways in diabetic nephropathy. J Am Soc Nephrol2003; 14: S241–S245

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