A Bayesian latent class model for integrating multi-source longitudinal data: application to the CHILD cohort study

Author:

Lu Zihang1ORCID,Subbarao Padmaja2,Lou Wendy3

Affiliation:

1. Department of Public Health Sciences & Department of Mathematics and Statistics, Queen’s University , Kingston, ON , Canada

2. Division of Respiratory Medicine, Department of Pediatrics, Hospital for Sick Children & University of Toronto , Toronto, ON , Canada

3. Dalla Lana School of Public Health, University of Toronto , Toronto, ON , Canada

Abstract

Abstract Multi-source longitudinal data have become increasingly common. This type of data refers to longitudinal datasets collected from multiple sources describing the same set of individuals. Representing distinct features of the individuals, each data source may consist of multiple longitudinal markers of distinct types and measurement frequencies. Motivated by the CHILD cohort study, we develop a model for joint clustering multi-source longitudinal data. The proposed model allows each data source to follow source-specific clustering, and they are aggregated to yield a global clustering. The proposed model is demonstrated through real-data analysis and simulation study.

Funder

Natural Sciences and Engineering Research Council of Canada

Canadian Institutes of Health Research Institute of Circulatory and Respiratory Health

Canadian Allergy, Asthma and Immunology Foundation

AstraZeneca Canada

Asthma Canada

Canadian Lung Association

Publisher

Oxford University Press (OUP)

Subject

Statistics, Probability and Uncertainty,Statistics and Probability

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