The natural compound obtusaquinone targets pediatric high-grade gliomas through ROS-mediated ER stress
Author:
Affiliation:
1. Experimental Therapeutics and Molecular Imaging Unit, Department of Neurology, Neuro-Oncology Division, Massachusetts General Hospital, Boston, Massachusetts, USA
2. Program in Neuroscience, Harvard Medical School, Boston, Massachusetts, USA
Abstract
Funder
National Institutes of Health
National Institute of Neurological Disorders and Stroke
Publisher
Oxford University Press (OUP)
Subject
Electrical and Electronic Engineering,Building and Construction
Link
http://academic.oup.com/noa/advance-article-pdf/doi/10.1093/noajnl/vdaa106/33689367/vdaa106.pdf
Reference27 articles.
1. Colorectal cancer statistics, 2020;Siegel;CA Cancer J Clin.,2020
2. Pediatric high-grade glioma: current molecular landscape and therapeutic approaches;Braunstein;J Neurooncol.,2017
3. Diffuse intrinsic pontine glioma treated with prolonged temozolomide and radiotherapy—results of a United Kingdom phase II trial (CNS 2007 04);Bailey;Eur J Cancer,2013
4. Diffuse intrinsic pontine glioma: poised for progress;Warren;Front Oncol.,2012
5. Misfolded proteins bind and activate death receptor 5 to trigger apoptosis during unresolved endoplasmic reticulum stress;Lam;eLife,2020
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1. The Role of the Ubiquitin Proteasome System in Glioma: Analysis Emphasizing the Main Molecular Players and Therapeutic Strategies Identified in Glioblastoma Multiforme;Molecular Neurobiology;2021-03-04
2. Pediatric glioblastoma - unlike normal cells - are sensitive to the combination of vorinostat and olaparib and to its downstream effector - phosphorylated eIF2α;2020-11-25
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