The Contribution of Neighborhood Socioeconomic Disadvantage to Depressive Symptoms Over the Course of Adult Life: A 32-Year Prospective Cohort Study

Author:

Elovainio Marko12,Vahtera Jussi34,Pentti Jaana34,Hakulinen Christian1,Pulkki-Råback Laura1,Lipsanen Jari1,Virtanen Marianna5,Keltikangas-Järvinen Liisa1,Kivimäki Mika67,Kähönen Mika89,Viikari Jorma31011,Lehtimäki Terho912,Raitakari Olli31011

Affiliation:

1. Department of Psychology and Logopedics, Faculty of Medicine, University of Helsinki, Helsinki, Finland

2. National Institute for Health and Welfare, Helsinki, Finland

3. Centre for Population Health Research, University of Turku and Turku University Hospital, Turku, Finland

4. Department of Public Health, Faculty of Medicine, University of Turku, Turku, Finland

5. School of Educational Sciences and Psychology, University of Eastern Finland, Joensuu, Finland

6. Department of Epidemiology and Public Health, Faculty of Population Health Sciences, University College London, London, United Kingdom

7. Clinicum Unit, Faculty of Medicine, University of Helsinki, Helsinki, Finland

8. Department of Clinical Physiology, Tampere University Hospital, Tampere, Finland

9. Finnish Cardiovascular Research Center–Tampere, Faculty of Medicine and Health Technology, Tampere University, Tampere, Finland

10. Research Centre of Applied and Preventive Cardiovascular Medicine, University of Turku, Turku, Finland

11. Department of Clinical Physiology and Nuclear Medicine, Turku University Hospital, Turku, Finland

12. Department of Clinical Chemistry, Fimlab Laboratories, Tampere, Finland

Abstract

Abstract The association between socioeconomic disadvantage and increased risk of depressive symptoms in adulthood is well established. We tested 1) the contribution of early exposure to neighborhood socioeconomic disadvantage to later depressive symptoms throughout life, 2) the persistence of the potential association between early exposure and depressive symptoms, and 3) the contributions of other known risk factors to the association. Data were collected from the Young Finns Study, a prospective, population-based 32-year follow-up study that included participants aged 3–18 years at baseline in 1980. Participants were followed up with repeated measurements of depressive symptoms between 1992 and 2012 (n = 2,788) and linked to national grid data on neighborhood disadvantage via residential addresses. We examined the associations in mixed models separately for the 5-, 10-, 15-, and 20-year follow-ups. Living in a disadvantaged neighborhood during childhood and adolescence was associated with a higher level of depressive symptoms in adulthood during all follow-up periods (β = 0.07, P = 0.001) than living in a nondisadvantaged area. Individual adulthood socioeconomic status mediated the associations. These findings suggest that living in a socioeconomically disadvantaged area during childhood and adolescence has a long-lasting negative association with mental health irrespective of family-related risks, partially due to socioeconomic adversity later in life.

Funder

Academy of Finland

Medical Research Council

National Institute on Aging

Amorfix Life Sciences

National Institutes of Health

Publisher

Oxford University Press (OUP)

Subject

Epidemiology

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