Guidelines for Thrombolytic Therapy for Frostbite

Author:

Hickey Sean1,Whitson Amy2,Jones Larry2,Wibbenmeyer Lucy3,Ryan Colleen4,Fey Ryan5,Litt Jeffrey6,Fabia Renata7,Cancio Lee8,Mohr William910,Twomey John11,Wagner Anne12,Cochran Amalia2ORCID,Bailey J Kevin13ORCID

Affiliation:

1. Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts

2. Department of Surgery, The Ohio State University, Columbus, Ohio

3. Department of Surgery, University of Iowa Hospitals and Clinics, Iowa City

4. Department of Surgery, Massachusetts General Hospital, Harvard Medical School Shriners Hospitals for Children-Boston

5. Department of Surgery, Hennepin County Medical Center, Minneapolis Minnesota

6. Department of Surgery, University of Missouri School of Medicine, Columbia, Missouri

7. Department of Pediatric Surgery, Nationwide Childrens Hospital, Columbus, Ohio

8. United States Army Institute of Surgical Research, Fort Sam Houston, Texas

9. Burn Center and Department of Trauma and General Surgery, Regions Hospital, St. Paul, Minnesota

10. Department of Surgery, University of Minnesota, Minneapolis

11. Department of Surgey, Hennepin County Medical Center, Minneapolis, Minnesota

12. Department of Surgery, University of Colorado School of Medicine, Aurora, Colorado

13. Department of Surgery, Wake Forest University School of Medicine, Medical Center Blvd, Winston-Salem, North Carolina

Abstract

Abstract The data are insufficient to support standardized treatment of all patients with frostbite with thrombolytic therapy. The following guidelines, however, should be applied to all patients with cyanosis persisting proximal to the distal phalanx (Grade 3 or 4 frostbite injury) and demonstrated loss of perfusion at or proximal to the middle phalanx immediately after rewarming.

Publisher

Oxford University Press (OUP)

Subject

Rehabilitation,Emergency Medicine,Surgery

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1. Cryotherapy-Induced Iatrogenic Frostbite on Distal Digit: Case Report and Review of Management Strategies;Military Medicine;2024-03-01

2. Frostbite incidence is a selective term and dependable on methodology — a narrative review;Health Promotion & Physical Activity;2024-02-28

3. Management of Frostbite Injury in Primary Care;The Journal for Nurse Practitioners;2024-02

4. Frostbite in the Pediatric Population;Pediatric Emergency Care;2024-01-11

5. The Occasional frostbite;Canadian Journal of Rural Medicine;2024

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