Severe acidosis due to 5-oxoprolinase inhibition by flucloxacillin in a patient with shoulder prosthesis joint infection-Reference-Cited by-同舟云学术

Severe acidosis due to 5-oxoprolinase inhibition by flucloxacillin in a patient with shoulder prosthesis joint infection

Published:2022-04-04 Issue:2 Volume:7 Page:71-74
ISSN:2206-3552
Container-title:Journal of Bone and Joint Infection
language:en
Short-container-title:J. Bone Joint Infect.

Author:

Lenz Julia Elisabeth^ORCID,Alt Volker^ORCID,Dienemann Thomas

Abstract

Abstract. We report a case of a 64-year-old female patient with severe metabolic acidosis. Inhibition of 5-oxoprolinase by flucloxacillin was found to be the cause of the metabolic derailment.

Publisher

Copernicus GmbH

Subject

Infectious Diseases,Orthopedics and Sports Medicine,Surgery

Link

https://jbji.copernicus.org/articles/7/71/2022/jbji-7-71-2022.pdf

Reference16 articles.

1. Adeva-Andany, M. M., Fernandez-Fernandez, C., Mourino-Bayolo, D., Castro-Quintela, E., and Dominguez-Montero, A.: Sodium bicarbonate therapy in patients with metabolic acidosis, Scientific World Journal, 2014, 627673, https://doi.org/10.1155/2014/627673, 2014.

2. Agrawal, A., Kishlyansky, M., Biso, S., Patnaik, S., and Punjabi, C.: Common, yet elusive: a case of severe anion gap acidosis, Oxf. Med. Case Reports, 2017, omx054, https://doi.org/10.1093/omcr/omx054, 2017.

3. Berbee, J. K., Lammers, L. A., Krediet, C. T. P., Fischer, J. C., and Kemper, E. M.: Metabolic acidosis caused by concomitant use of paracetamol (acetaminophen) and flucloxacillin? A case report and a retrospective study, Eur. J. Clin. Pharmacol., 73, 1459–1465, https://doi.org/10.1007/s00228-017-2311-6, 2017.

4. Emmett, M.: Acetaminophen toxicity and 5-oxoproline (pyroglutamic acid): a tale of two cycles, one an ATP-depleting futile cycle and the other a useful cycle, Clin. J. Am. Soc. Nephrol., 9, 191–200, https://doi.org/10.2215/CJN.07730713, 2014.

5. Hundemer, G. L. and Fenves, A. Z.: Acquired 5-oxoproline acidemia successfully treated with N-acetylcysteine, Proc (Bayl Univ Med Cent), 30, 169–170, https://doi.org/10.1080/08998280.2017.11929570, 2017.

Cited by 2 articles. 订阅此论文施引文献订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献

1. Flucloxacillin/Hydrocortisone;Reactions Weekly;2024-03-09

2. Pyroglutamate acidosis 2023. A review of 100 cases;Clinical Medicine;2024-03