Two novel linkage SNPs of VLDLR gene intron 11 are associated with laying traits in two quail populations
-
Published:2015-03-04
Issue:1
Volume:58
Page:1-6
-
ISSN:2363-9822
-
Container-title:Archives Animal Breeding
-
language:en
-
Short-container-title:Arch. Anim. Breed.
Author:
Wu Y.,Pi J. S.,Pan A. L.,Du J. P.,Shen J.,Pu Y. J.,Liang Z. H.
Abstract
Abstract. The very low density lipoprotein receptor (VLDLR) is an important multifunctional receptor and plays a key role in chicken reproduction. This study is designed to investigate the effect of variants in the VLDLR gene on quail laying traits. Two quail populations were studied – yellow feather quail and chestnut feather quail; 384 individuals per breed were used. The laying traits (the weight of the first egg, the age of the first egg, egg weight, the weight of 20-week-old and the egg number of 20-week-old) were measured and recorded. The polymerase chain reaction–restriction fragment length polymorphism (PCR-RFLP) method was developed to genotype those individuals. The results showed two novel polymorphisms, i.e. two linkage variations in intron 11 of the VLDLR gene (363T > C and 392C > T). They are associated with the weight of the first egg, the age of the first egg and egg number of 20-week-old in yellow feather and chestnut feather quail. The two variations in intron 11 of VLDLR may be linked with potential major loci or genes affecting some laying traits.
Publisher
Copernicus GmbH
Reference22 articles.
1. Agulleiro, M. J., André, M., Morais, S., Cerdà, J., and Babin, P. J.: High Transcript Level of Fatty Acid-Binding Protein 11 but Not of Very Low-Density Lipoprotein Receptor Is Correlated to Ovarian Follicle Atresia in a Teleost Fish (Solea senegalensis), Biol. Reprod., 77, 504–516, 2007. 2. An, X. P., Hou, J. X., Li, G., Song, Y. X., Wang, J. G., Chen, Q. J., Cui, Y. H., Wang, Y. F., and Cao, B. Y.: Polymorphism identification in the goat KITLG gene and association analysis with litter size, Anim. Genet., 43, 104–107, 2011. 3. Barber, D. L., Sanders, E. J., Aebersold, R., and Schneider, W. J.: The receptor for yolk lipoprotein deposition in the chicken oocyte, J. Biol. Chem., 266, 18761–18770, 1991. 4. Bujo, H., Hermann, M., Kaderli, M. O., Jacobsen, L., Sugawara, S., Nimpf, J., Yamamoto, T., and Schneider, W. J.: Chicken oocyte growth is mediated by an eight ligand binding repeat member of the LDL receptor family, EMBO J., 13, 5165–5175, 1994. 5. Bujo, H., Yamamoto, T., Hayashi, K., Hermann, M., Nimpf, J., and Schneider, W. J.: Mutant oocytic low density lipoprotein receptor gene family member causes atherosclerosis and female sterility, P. Natl. Acad. Sci. USA, 92, 9905–9909, 1995.
Cited by
4 articles.
订阅此论文施引文献
订阅此论文施引文献,注册后可以免费订阅5篇论文的施引文献,订阅后可以查看论文全部施引文献
|
|