Apports de la chémo-informatique dans la recherche et l’optimisation des molécules d’intérêt thérapeutique
Author:
Publisher
EDP Sciences
Subject
General Biochemistry, Genetics and Molecular Biology,General Medicine
Link
http://www.medecinesciences.org/10.1051/medsci/20092510871/pdf
Reference17 articles.
1. Walters WP, Stahl MT, Murcko MA. A virtual screening: an overview.Drug Discov Today1998; 3 : 160–78.
2. Shoichet BK. Virtual screening of chemical librairies.Nature2004; 432 : 862–5.
3. Hristozov DP, Oprea TI, Gasteiger J. Virtual screening applications: a study of ligand based methods and different structure representations in four different scenarios.J Comput Aided Mol Des2007; 21 : 617–40.
4. Lipinsky CA. Lead to drug like compounds : the rule of five revolution drug like properties.Drug Discov Today2004; 1 : 337–41.
5. Opera T. Property distribution of drug-related chemical databases.J Comput Aid Mol Des2000; 14 : 251–64.
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