Protéine de fusion ou anticorps monoclonal

Author:

Sibilia Jean

Publisher

EDP Sciences

Subject

General Biochemistry, Genetics and Molecular Biology,General Medicine

Reference49 articles.

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2. Haak-Frendscho M, Marsters SA, Mordenti J,et al.Inhibition of TNF by a TNF receptor immunoadhesin. Comparison to an anti-TNF monoclonal antibody.J Immunol1994; 152 : 1347–53.

3. Butty VL, Roux-Lombard P, Garbino J,et al.Geneva Sepsis Network. Anti-inflammatory response after infusion of p55 soluble tumor necrosis factor receptor fusion protein for severe sepsis.Eur Cytokine Netw2003; 14 : 15–9.

4. Abraham E, Laterre PF, Garbino J,et al.Lenercept (p55 tumor necrosis factor receptor fusion protein) in severe sepsis and early septic shock: a randomized, double-blind, placebo-controlled, multicenter phase III trial with 1,342 patients.Crit Care Med2001; 29 : 503–10.

5. Rau R, Sander O, van Riel P,et al.Intravenous human recombinant tumor necrosis factor receptor p55-Fc IgG1 fusion protein Ro 45-2081 (lenercept): a double blind, placebo controlled dose-finding study in rheumatoid arthritis.J Rheumatol2003; 30 : 680–90.

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