Le ranélate de strontium, nouvel agent thérapeutique dans l’ostéoporose post-ménopausique
Author:
Publisher
EDP Sciences
Subject
General Biochemistry, Genetics and Molecular Biology,General Medicine
Link
http://www.medecinesciences.org/10.1051/medsci/2004206-7631/pdf
Reference6 articles.
1. Shorr E, Carter AC. The usefulness of strontium as an adjuvant to calcium in the remineralization of the skeleton in man.Bull Hosp Joint Dis1952; 13 : 59–66.
2. Marie PJ, Ammann P, Boivin G, Rey C. Mechanisms of action and therapeutic potential of strontium in bone.Calcif Tissue Int2001; 69 : 121–9.
3. Boivin G, Deloffre P, Perrat B,et al.Strontium distribution and interactions with bone mineral in monkey iliac bone after strontium salt (5 12911) administration.J Bone Miner Res1996; 9 : 1302–11.
4. Meunier PJ, Slosman DO, Delmas PD,et al.Strontium ranelate : dose-dependent effects in established postmenopausal vertebral osteoporosis – A 2-year randomised placebo controlled trial.J Clin Endocrinol Metab2002; 87 : 2060–6.
5. Meunier PJ, Roux C, Seeman E,et al.The effects of strontium ranelate on the risk of vertebral fracture in women with postmenopausal osteoporosis.N Engl J Med2004; 350 : 459–68.
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2. Activation of FGF Receptors is a new Mechanism by which Strontium Ranelate Induces Osteoblastic Cell Growth;Cellular Physiology and Biochemistry;2011
3. Strontium ranelate promotes osteoblastic cell replication through at least two different mechanisms;Bone;2008-06
4. New Strategies for the Treatment of Metastatic Bone Disease;Clinical Breast Cancer;2007-12
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