Digital Twin for biological safety cabinet to reproduce performance and field certification test specified by NSF/ANSI 49 - 2019

Author:

Muta Ryota,Ito Kazuhide

Abstract

The airflow balance test to confirm the physical performance of biological safety cabinets (BSC) is standardized by JIS K 3800 in accordance with NSF/ANSI 49 in Japan. In the test, Bacillus atrophaeus spores are used as an evaluation index, which poses a few limitations, such as their dependence on the environmental conditions to be tested. The aim of this study is to develop BSC digital twins and discuss reasonable alternatives for performance evaluation tests while maintaining the accuracy of the bacterial test performance. Herein, we provide the outline of a digital twin model for BSCs and the results of a numerical analysis, where a passive scalar is used as an alternative pollutant in the evaluation index.

Publisher

EDP Sciences

Subject

General Medicine

Reference3 articles.

1. Japanese Standards Association, Class II biological safety cabinets JIS K 3800 (JACA/JSA), (2021)

2. Impact of heat generation and use of experimental instruments in a fume hood on pollutant capture efficiency

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