Current status and content of quantitative criteria in clinical trials of compression therapy

Author:

Lei Congcong,Chen Lu

Abstract

Objective: The scale of the treatment effect of lymphedema pressure has not been clarified, and there appears to be a lack of evidence for research in this area. There is no clear and uniform standard for measuring the experimental results of lymphedema treatment with pressure clothing, and there seems to be a lack of research on the experimental results measure. The purpose of this study was to summarize and quality evaluate the existing scientific evaluation criteria for the therapeutic measure of upper limb compression. To review the differences and similarities in efficacy evaluation criteria of pressure cuff, pressure bandage, CDT and other treatment methods. And some new ideas. Methods: Narrative review based on search in Pub-Med/Web of Science through keywords related to compression in lymphedema. A systematic review of published literature was performed. Results: In the review, 1716 articles were screened, of which 11 trials were included. The primary end point of the assessment and results was to measure changes in arm volume, secondary endpoints were the quality of life, patient compliance, range of motion of arm joints and other reason. Although the effectiveness of compression therapy can be obtained by comparing experiments, there is no uniform measurement of experimental results, so it is impossible to compare the effectiveness between different experiments. Conclusions: At present, in the treatment of lymphedema, the effect of the pressurized sleeve is recognized, and the accepted measure is the change in arm volume, and secondary criteria vary widely. The available literature lacks a unified measurement standard for experimental results and measurement items. Researchers should combine the actual situation of the local patients with lymphedema to construct a suitable measure of the effect of lymphedema compression treatment after breast cancer.

Publisher

EDP Sciences

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