The effectiveness of a feed additive with galloisite in rat mycotoxicosis

Author:

Tarasova Evgenya,Matrosova Lilia,Kashevarov Gleb,Tanaseva Svetlana,Ermolaeva Olga,Sofronova Anastasia,Mishina Nailya,Valiullin Lenar,Mukhammadiev Rishat,Semenov Eduard

Abstract

The paper presents the results of assessing the effectiveness of a complex feed additive based on halloysite for experimental T-2, afla- and zearalenone toxicosis of white rats in terms of survival, changes in clinical condition, enzyme status of blood serum and spleen ultrastructure. The results presented in the article confirmed the danger of the combined effects of mycotoxins on the body of white rats. The presence of mycotoxins in the feed led to the death of 30.0% of rats with a change in the clinical condition of the surviving animals, a significant increase in the serum levels of aminotransferases, alkaline phosphatase, lactate dehydrogenase, creatine kinase and gamma-glutamyltransferase, as well as changes in the ultrastructure of the spleen. A normalizing effect of a food additive based on halloysite on the studied parameters in experimental combined mycotoxicosis was noted, which was manifested by 100% survival of rats, less pronounced changes in the enzyme status and a protective effect on the ultrastructure of the spleen. This makes it promising for further comprehensive research on productive animal species with the prospect of implementation in animal husbandry as an effective means of preventing combined mycotoxicoses.

Publisher

EDP Sciences

Reference41 articles.

1. You Y., Qiu Y., Xu H., He R., Zhang L., Wang Z., Xia Y., Food Biosci. 59 (2024)

2. Lee J.T., Jessen K.A., Beltran R., Starkl V., Schatzmayr G., Borutova R., Caldwell D.J., Poult. Sci. 91 (2012)

3. Kolawole O., Siri-Anusornsak W., Petchkongkaew A., Elliott C., Emerging Contaminants 10 (2024)

4. Mihalache O.A., Torrijos R., Dall'Asta C., Environ. Int. 185 (2024)

5. Akhmedov A., Gamirov R., Panina Yu., Sokolova E., Leonteva Yu., Tarasova E., Potekhina R., Fitsev I., Shurpik D., Stoikov I., Org. Biomol. Chem. 23 (2023)

同舟云学术

1.学者识别学者识别

2.学术分析学术分析

3.人才评估人才评估

"同舟云学术"是以全球学者为主线,采集、加工和组织学术论文而形成的新型学术文献查询和分析系统,可以对全球学者进行文献检索和人才价值评估。用户可以通过关注某些学科领域的顶尖人物而持续追踪该领域的学科进展和研究前沿。经过近期的数据扩容,当前同舟云学术共收录了国内外主流学术期刊6万余种,收集的期刊论文及会议论文总量共计约1.5亿篇,并以每天添加12000余篇中外论文的速度递增。我们也可以为用户提供个性化、定制化的学者数据。欢迎来电咨询!咨询电话:010-8811{复制后删除}0370

www.globalauthorid.com

TOP

Copyright © 2019-2024 北京同舟云网络信息技术有限公司
京公网安备11010802033243号  京ICP备18003416号-3