Author:
Saitkulov Foziljon,Sapaev Bairamdurdi,Nasimov Khasan,Kurbanova Dilorom,Tursunova Nargiza
Abstract
The government has emphasized the significance of making significant investments in scientific research to develop herbicides, fungicides, bactericides, anthelmintic agents, weed and pest control agents, and alternative pesticides that are eco-friendly and can be exported. In this research, the aromaticity of quinazolin-4-one a and p was studied. A one-stage method for obtaining quinazolin-4-one a was developed by condensation of anthranilic acid and formamide when heated to Wood's alloy. Quinazolin-4-one exhibits conformity with Hückel's rules upon undergoing a reaction with alkali metals, hydrides, and alkalis. An investigation was performed to assess the aromaticity of both para and ortho quinazolin-4-one. Quinazolin-4-one a was obtained through a one-step process, which involved condensing anthranilic acid and formamide using Wood's alloy at a temperature of 130-135 ºС for two hours, which was found to be optimal.