Abstract
Multiple studies have shown a relationship between EO exposure and an increased risk of cancer in humans, but the results have been inconsistent. Nonetheless, the association between EO and human cancer risk, especially in terms of dose-response, is poorly understood. Examining whether or not EO exposure is linked to increased cancer risk in the basic adult population in the U.S. was the primary focus of this study. The study included data from both the 2013–14 and 2015–16 waves of the National Health and Nutrition Examination Survey (NHANES), for a total of 3,448 people. Data including demographic characteristics, medical history, and serum EO biomarkers were retrieved from Serum EO biomarker (hemoglobin adduct of EO (HbEO)) concentrations evaluated. Odds ratios (ORs) and 95% confidence intervals (CIs) were determined by multiple logistic regression. The result shows that EO with the highest concentration between 1340 and 1780(OR = 19.12, 95% CI: 1.73-211.47) is statistically significant.