Abstract
Liposomes, as biocompatible and safe nanocarriers with easily modified surfaces, can be well used in the field of antitumor. Their targeting properties have contributed to the reduction of drug dosage and non-target cell toxicity. To further exploit the targeting properties of liposomes, passive targeting liposomes, active targeting liposomes and physicochemical targeting liposomes have been constructed by surface modification. This paper summarizes the mechanisms of action of different types of targeted liposomes and describes the specific role of liposomes in overcoming tumor resistance, immunotherapy and helping drugs to cross the blood-brain barrier, and summarizes the current development issues and future directions.
Reference85 articles.
1. Jianxiong Li, Shuang Geng, Hu Shujian et al. Advances in functional structure design and applications of liposome delivery systems. Advances in Chemical Engineering. p. 1-12.
2. A detailed insight of the tumor targeting using nanocarrier drug delivery system
3. Recent advances in liposome formulations for breast cancer therapeutics