Author:
Aljuboory Dhuha Salman,Sharba Intisar Razzaq
Abstract
Acute leukemia (ALL and AML) has an adverse effect hemostasis. Coagulopathy is a common comorbidity in patients with acute leukemia. When compared patients with control the result showed highly significant (p-value<0.05) increase in acute leukemia patients as compared control group in mean of PDGF-BB level, ANXA level, D-Dimer level, H3 . Comparison characteristic parameter between acute leukemia patients groups founded significant increase in age, PDGF-BB, D-Dimer and ANXA2 in AML patients more than ALL patients group. H3 and showed no significant difference between AML and ALL patients groups. The ROC curve analysis and AUC for study biomarkers to diagnosis between acute leukemia patients group showed highly positive significant (p-value <0.05) predictive value with PGDF-BB followed by D-Dimer, ANXA2 then H3