Effects of Sidempuan Salacca (Salacca sumatrana) Vinegar on Hyperuricemia: Histopathological Assessment

Abstract

This research aimed to ascertain the effectiveness of Sidempuan salacca vinegar on improving kidney degeneration in hyperuricemia male mice. The mice were grouped into untreated mice, hyperuricemia mice without treatment, and hyperuricemia mice treated with Sidempuan salacca vinegar. The blood uric acid was measured by Easy Touch GCU, and the histopathology of the kidney was observed using the paraffin method and HE staining. The results demonstrated that Sidempuan salacca vinegar has the ability to decrease blood uric acid significantly. Sidempuan Salacca vinegars have the ability for regeneration in addition to kidney cells. However, the capacity of P3 to regulate hyperuricemia seemed to be better than that of other treatments. Sidempuan salacca vinegar has the potential to be used therapeutically by reducing tissue damage in hyperuricemic mice.