Asymmetric field flow fractionation applied to the nanoparticles characterization: Study of the parameters governing the retention in the channel

Abstract

In this work we study the parameters which are often modified to optimize the separation in asymmetrical field flow fractionation, and we observe their impact on the retention behavior of the analyte. The aim of the work is to improve our knowledge of the phenomena which govern the behavior of the analytes in the channel and to have a better understanding of the limits of the actual theoretical model in order to improve it. Results illustrate that the ionic strength influences the effect of the cross flow rate on the retention time of the particle. The question of the determination of the channel thickness was also addressed.