Standardisation of 18F using new portable 4πβ(LS) – λ coincidence detection system at ENEA-INMRI

Abstract

This project concerned with the development at ENEA-INMRI of new in-situ 4πβ(LS) − λ coincidence detection system for activity measurement of the short half-life radionuclides used in Nuclear Medicine. The hardware of the new portable 4πβ(LS) − λ coincidence detection system was implemented at ENEA-INMRI, in collaboration with Catania University and INFN, by adding a gamma channel on the existing TDCR portable detector available at ENEA-INMRI. A new data analysis software was developed at CAEN, independently from an existing one elaborated at ENEA.INMRI, in order to analyse the data recorded in list-mode by the new detector equipped with the CAEN desktop digitizer DT5720. The activity for short half-life radionuclides used in nuclear medicine can be then computed. Two primary activity measurement TDCR and 4πβ(LS) − λ coincidence methods were then used to determine the activity of 18F at ENEA-INMRI. The TDCR parameter is measured for the 18F standard solution using both CAEN and ENEA-INMRI data analysis software.