Facile fabrication of silicon coating for improving biodegradation and cytocompatibility of pure magnesium by hydrothermal method

Author:

Ma Liyan,Niu Jia

Abstract

In this study, a bioactive silicon coating was fabricated for reducing the degradation rate and enhancing the cytocompatibility of the pure magnesium. The morphology and phase of coating were characterized by a scanning electron microscope (SEM), energy-dispersive X-ray spectroscopy (EDS), X-ray diffractometer (XRD), and X-ray photoelectron spectroscopy (XPS), respectively. The electrochemical and immersion tests were conducted in a simulated body fluid to evaluate the in vitro degradation behavior of the Si-coated sample. Cell viability and cell adhesion assays of human osteosarcoma cells were performed to determine the biocompatibility of the Si-coating. The XRD pattern suggested that MgO, Mg2SiO4 and SiO2 were formed on the Si-coated sample. The results of the electrochemical and immersion tests showed that the Si-coating could significantly decrease degradation rate of the pure magnesium. Meanwhile, the Si-coating could significantly promote the cell adhesion, migration and proliferation in vitro. It is considered that the Si-coating showed a promising application in improving the anticorrosion and biocompatibility of the pure magnesium.

Funder

Science and technology department project of Fujian

Publisher

EDP Sciences

Subject

Materials Chemistry,Metals and Alloys,Mechanics of Materials,Computational Mechanics

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