A rare case of cytomegalovirus induced oral ulcer in an immunocompromised patient

Abstract

Introduction: Oral manifestations of cytomegalovirus are rare. Observation: We report the case of an atypical and persistent oral location of cytomegalovirus, in the form of ulcers, in a patient suffering from granulomatosis with polyangiitis and treated by rituximab. Discussion: In front of a chronic ulcer, a differential diagnosis must be made to exclude different etiologies, by order of severity, frequency or according to the clinical situation of the patient. The main differential diagnosis that must be excluded is a squamous-cell carcinoma. Conclusion: Cytomegalovirus ulcers are not specific and its etiology cannot be affirmed clinically. A pathological examination is essential to allow the quick establishing of a treatment in an immuno-compromised patient to prevent further complications.