Cardiopulmonary Bypass for A Patient with Systemic Mastocytosis

Abstract

A patient with systemic mastocytosis was seen in our practice for coronary revascularization. Systemic mastocytosis is a disease characterized by proliferation of mast cells which, under stress, are likely to release vasoactive substances. Coronary artery bypass grafting, utilizing cardiopulmonary bypass with moderate hypothermia, resulted in no clinical problems attributable to this rare pathology. Steps to lessen or eliminate stresses likely to precipitate problems associated with histamine release are discussed.