Barriers and solutions to finding rifampicin-resistant tuberculosis cases in older children and adolescents

Author:

Mohr-Holland E.1,Apolisi I.2,Reuter A.2,de Azevedo V.3,Hill J.4,Matthee S.5,Seddon J. A.6,Isaakidis P.7,Furin J.8,Trivino-Duran L.2

Affiliation:

1. Médecins Sans Frontières (MSF), Khayelitsha and Cape Town, South Africa, Southern Africa Medical Unit, MSF, Cape Town, South Africa

2. Médecins Sans Frontières (MSF), Khayelitsha and Cape Town, South Africa

3. City Health Department, Cape Town, South Africa

4. Technical Division, KNCV Tuberculosefonds, The Hague, Netherlands

5. Provincial Government of the Western Cape Health Department, Cape Town, South Africa

6. Desmond Tutu TB Centre, Department of Paediatric and Child Health, Faculty of Medicine and Health Sciences, Stellenbosch University, Cape Town, South Africa, Department of Paediatrics, Imperial College London, London, UK

7. Southern Africa Medical Unit, MSF, Cape Town, South Africa

8. Harvard Medical School, Department of Global Health and Social Medicine, Boston, MA, USA

Abstract

Little is known about the barriers to post-exposure management of rifampicin-resistant tuberculosis (RR-TB) in older children and adolescents. We report on implementation lessons from a pilot programme targeting household-exposed individuals aged 6–18 years in Khayelitsha, South Africa. Barriers included misperceptions regarding risk of exposure, multiple research and implementation stakeholders, additional workload for an overburdened healthcare system, logistical issues faced by families, and insufficient human and financial resources. Solutions to these barriers are possible, but creativity and persistence are required. Our experience can guide others looking to roll-out care for children and adolescents exposed to RR-TB.

Publisher

International Union Against Tuberculosis and Lung Disease

Subject

Public Health, Environmental and Occupational Health,Health Policy

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