Diabetes characteristics and long-term management needs in diabetic TB patients-Reference-Cited by-同舟云学术

Diabetes characteristics and long-term management needs in diabetic TB patients

Published:2023-02-01 Issue:2 Volume:27 Page:113-120
ISSN:1027-3719
Container-title:The International Journal of Tuberculosis and Lung Disease
language:en
Short-container-title:int j tuberc lung dis

Author:

Koesoemadinata R. C.¹,McAllister S. M.²,Soetedjo N. N. M.³,Santoso P.³,Dewi N. F.⁴,Permana H.³,Ruslami R.⁵,Alisjahbana B.³,Critchley J. A.⁶,Dockrell H. M.⁷,Hill P. C.²,van Crevel R.⁸

Affiliation:

1. Research Center for Care and Control of Infectious Disease, Universitas Padjadjaran, Bandung, Indonesia, Department of Internal Medicine, Radboud Institute of Health Sciences, Radboud University Medical Center, Nijmegen, The Netherlands

2. Centre for International Health, Division of Health Sciences, University of Otago Medical School, Dunedin, New Zealand

3. Research Center for Care and Control of Infectious Disease, Universitas Padjadjaran, Bandung, Indonesia, Department of Internal Medicine, Faculty of Medicine, Universitas Padjadjaran/ Dr Hasan Sadikin General Hospital, Bandung, Indonesia

4. Research Center for Care and Control of Infectious Disease, Universitas Padjadjaran, Bandung, Indonesia

5. Research Center for Care and Control of Infectious Disease, Universitas Padjadjaran, Bandung, Indonesia, Department of Biomedical Science, Faculty of Medicine, Universitas Padjadjaran, Bandung, Indonesia

6. Population Health Research Institute, St George´s University of London, London, UK

7. Faculty of Infectious and Tropical Diseases and Tuberculosis Centre, London School of Hygiene & Tropical Medicine, London, UK

8. Department of Internal Medicine, Radboud Institute of Health Sciences, Radboud University Medical Center, Nijmegen, The Netherlands, Centre for Tropical Medicine and Global Health, Nuffield Department of Medicine, University of Oxford, Oxford, UK

Abstract

BACKGROUND: Diabetes mellitus (DM) is common among patients with TB. We assessed DM characteristics and long-term needs of DM-TB patients after completing TB treatment.METHODS: Newly diagnosed TB patients with DM were recruited for screening in a randomised clinical trial evaluating a simple algorithm to improve glycaemic control during TB treatment. DM characteristics, lifestyle and medication were compared before and after TB treatment and 6 months later. Risk of cardiovascular disease (CVD), albuminuria and neuropathy were assessed after TB treatment.RESULTS: Of 218 TB-DM patients identified, 170 (78%) were followed up. Half were males, the mean age was 53 years, 26.5% were newly diagnosed DM. High glycated haemoglobin at TB diagnosis (median 11.2%) decreased during TB treatment (to 7.4% with intensified management and 8.4% with standard care), but this effect was lost 6 months later (9.3%). Hypertension and dyslipidemia contributed to a high 10-year CVD risk (32.9% at month 6 and 35.5% at month 12). Neuropathy (33.8%) and albuminuria (61.3%) were common. After TB treatment, few patients used CVD-mitigating drugs.CONCLUSION: DM in TB-DM patients is characterised by poor glycaemic control, high CVD risk, and nephropathy. TB treatment provides opportunities for better DM management, but effort is needed to improve long-term care.

Publisher

International Union Against Tuberculosis and Lung Disease

Subject

Infectious Diseases,Pulmonary and Respiratory Medicine

Cited by 3 articles. 订阅此论文施引文献订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献

1. Tuberculosis and diabetes mellitus: The current state of the problem;Vrach;2023-08-08

2. Why TB programmes should assess for comorbidities, determinants and disability at the start and end of TB treatment;The International Journal of Tuberculosis and Lung Disease;2023-07-01

3. Diabetes mellitus and TB – finding strategies to reduce the double burden of disease;The International Journal of Tuberculosis and Lung Disease;2023-02-01