TB and interstitial lung disease: a systematic review and meta-analysis-Reference-Cited by-同舟云学术

TB and interstitial lung disease: a systematic review and meta-analysis

Published:2024-03-01 Issue:3 Volume:28 Page:130-135
ISSN:1027-3719
Container-title:The International Journal of Tuberculosis and Lung Disease
language:en
Short-container-title:int j tuberc lung dis

Author:

Rezaee M.¹,Azizi N.²,Danaei B.¹,Davari A.²,Nejadghaderi S. A.¹,Sarmastzadeh T.¹,Rahmannia M.¹,Khalili F.¹,Shahidi-Bonjar A. H.³,Centis R.⁴,D’Ambrosio L.⁵,Sotgiu G.⁶,Migliori G. B.⁴,Nasiri M. J.⁷

Affiliation:

1. School of Medicine, Shahid Beheshti University of Medical Sciences, Tehran,

2. School of Medicine, Tehran University of Medical Sciences, Tehran,

3. Dental Materials and Restorative Dentistry, School of Dentistry, Shahid Beheshti University of Medical Sciences, Tehran, Iran;

4. Servizio di Epidemiologia Clinica delle Malattie Respiratorie, Istituti Clinici Scientifici Maugeri Istituto di Ricovero e Cura a Carattere Scientifico, Tradate, Italy;

5. Public Health Consulting Group, Lugano, Switzerland;

6. Unità di Epidemiologia Clinica e Statistica Medica, Dipartimento di Scienze Mediche Chirurgiche e Sperimentali, Università degli Studi di Sassari, Sassari, Italy;

7. Department of Microbiology, School of Medicine, Shahid Beheshti University of Medical Sciences, Tehran, Iran

Abstract

<sec id="st1"><title>INTRODUCTION</title>To determine the frequency of TB among patients with interstitial lung diseases (ILDs).</sec><sec id="st2"><title>METHODS</title>We performed a comprehensive search in the PubMed/Medline, EMBASE and Scopus databases up to 1 August 2023 of studies reporting on the prevalence of TB among patients with ILDs.</sec><sec id="st3"><title>RESULTS</title>Twelve studies comprising 3,817 patients with ILD were found: the pooled prevalence of TB among ILD patients was 11.0% (95% CI 5.4–21.0). In the subgroup analysis, the TB rate among patients with silicosis and idiopathic pulmonary fibrosis (IPF) was respectively 35.6% (95% CI 32.6–38.8) and 4.4% (95% CI 3.6–5.3) (P = 0.00). The frequency of TB among ILD patients was higher in high TB burden countries than in low/intermediate-burden countries: 26.3%, 95% CI 17.7–37.3 vs. 4.9%, 95% CI 3.3–7.2; P = 0.00.</sec><sec id="st4"><title>CONCLUSIONS</title>This study shows the frequency of TB among ILD patients. The meta-analysis reveals a significantly increased prevalence of TB among ILD patients with silicosis compared to IPF, and among individuals in high TB burden countries than in those with low/intermediate burden. The study results can help physicians and policymakers make efficient decisions for prompt screening and anti-TB treatment initiation in ILD patients.</sec>

Publisher

International Union Against Tuberculosis and Lung Disease