Increase in rifampicin resistance among people previously treated for TB-Reference-Cited by-同舟云学术

Increase in rifampicin resistance among people previously treated for TB

Published:2023-03-21 Issue:1 Volume:13 Page:4-6
ISSN:2220-8372
Container-title:Public Health Action
language:en
Short-container-title:public health action

Author:

Izudi J.¹,Bajunirwe F.²,Cattamanchi A.³

Affiliation:

1. Department of Community Health, Mbarara University of Science and Technology, Mbarara, Uganda, Infectious Diseases Institute, College of Health Sciences, Makerere University, Kampala, Uganda

2. Department of Community Health, Mbarara University of Science and Technology, Mbarara, Uganda

3. Division of Pulmonary Diseases and Critical Care Medicine, University of California Irvine, Irvine, CA, USA, Center for Tuberculosis, San Francisco General Hospital, University of California San Francisco, San Francisco, CA, USA

Abstract

People previously treated for TB are at a higher risk of rifampicin-resistant or multidrug-resistant TB (RR/MDR-TB). Uganda’s recent RR-TB estimates were not updated, including during the COVID-19 pandemic. Using programmatic data (2012–2021), we report on the distribution and trends in RR-TB among people previously treated for bacteriologically confirmed pulmonary TB (BC-PTB) across six TB clinics in Kampala, Uganda. The RR-TB prevalence between 2012 and 2015 was 0% (95% CI 0–2.3). The prevalence rose significantly in recent years to 7.0% (95% CI 4.4–10.8) between 2016 and 2021 (P < 0.001). RR-TB is increasing among people previously treated for BC-PTB in Kampala; surveillance for RR-TB should be enhanced.

Publisher

International Union Against Tuberculosis and Lung Disease

Subject

Public Health, Environmental and Occupational Health,Health Policy

Reference1 articles.

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