Delivery of TB preventive therapy to incarcerated people living with HIV in southern African correctional facilities

Author:

Chimoyi L.1,Smith H.2,Hausler H.3,Fielding K.4,Hoffmann C. J.5,Herce M. E.6,Charalambous S.7

Affiliation:

1. The Aurum Institute, Parktown, Johannesburg, South Africa

2. Centre for Infectious Disease Research in Zambia, Lusaka, Zambia, School of Population Health, University of New South Wales, Sydney, NSW, Australia

3. TB HIV Care, Cape Town, South Africa

4. London School of Tropical Hygiene & Medicine, London, UK

5. The Aurum Institute, Parktown, Johannesburg, South Africa, Johns Hopkins University, Baltimore, MD, USA

6. Centre for Infectious Disease Research in Zambia, Lusaka, Zambia, Institute for Global Health & Infectious Diseases, University of North Carolina School of Medicine, Chapel Hill, NC, USA

7. The Aurum Institute, Parktown, Johannesburg, South Africa, School of Public Health, University of the Witwatersrand, Johannesburg, South Africa

Abstract

TB preventive treatment (TPT) is recommended for high-risk and hard-to-reach populations such as incarcerated people living with HIV (PLHIV). To assess implementation of TPT delivery in correctional settings, we conducted an exploratory analysis of data from a multisite cohort study in South Africa and Zambia. From 975 participants, 648 were screened for TB, and 409 initiated TPT mostly within a month after initiation of antiretroviral therapy (190/409, 46.5%). We observed a median gap of one month (IQR 0.6–4.7) in TPT delivery to incarcerated PLHIV. Future research should examine standardised quality improvement tools and new strategies such as short-course regimens to improve TPT initiation in this population.

Publisher

International Union Against Tuberculosis and Lung Disease

Subject

Public Health, Environmental and Occupational Health,Health Policy

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