Affiliation:
1. Mazandaran University of Medical Sciences
2. Islamic Azad University
Abstract
The main purpose of this study is to synthesize nano-hydroxyapatite/cellulose (nHAP/Cel) and nano-hydroxyapatite/chitosan (nHAP/CS) scaffolds via co-precipitation method for bone tissue engineering due to their suitable biocompatibility, cytotoxicity and mechanical properties. The characterizations of these scaffolds were investigated by Infrared absorption spectra (FT-IR), X-ray Diffraction (XRD), and Scanning Electron Microscope (SEM). The cytotoxicity of these nanoparticles was evaluated with bone marrow cell using the 3-(4, 5-Dimethylthiazol-2-yl)-2, 5-diphenyl-tetrazoliumbromide) (MTT) assay. The porosity of scaffolds was estimated 87%. The results indicate that the nano composite scaffolds have good morphology, tissue biocompatibility and biodegradability to be used for tissue engineering.
Publisher
Trans Tech Publications, Ltd.
Reference27 articles.
1. Fabrication of Hydroxyapatite/Cellulose Fiber Composite with Sheet-Like Structure;Watanabe;Key Engineering Materials,2018
2. Biomimetic porous scaffolds for bone tissue engineering;Wu;Materials Science and Engineering: R: Reports
3. Nano-hydroxyapatite/chitosan–starch nanocomposite as a novel bone construct: Synthesis and in vitro studies;Shakir;International Journal of Biological Macromolecules
4. M Seyedsajadi, F Fathi , A Review of the properties, synthesis and application of Nano Hydroxyapatite, Int J Bio-Inorg Hybr Nanomater,( 2019) 8(1),5-25.
5. Preparation and characterization of thermally stable nanohydroxyapatite;ZHANG;Journal of Materials Science: Materials in Medicine
Cited by
1 articles.
订阅此论文施引文献
订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献