Evaluation of Newly Formulated Chlorhexidine Mouthwash

Author:

Tua-Ngam Peerapong1,Srichan Ratchaporn1,Klaophimai Arthit1,Rudrakanjana Pachara1,Wuttihasa Thanattha1,Kaypetch Rattiporn1

Affiliation:

1. Mahidol University

Abstract

Chlorhexidine gluconate mouthwash has a poor taste during and after rinsing which makes its users dissatisfied. Therefore, the product must be improved to have a better taste and still retain its effectiveness against oral pathogens. To evaluate in vitro antimicrobial activity and toxicity effects of Newly formulated chlorhexidine mouthwash. The antimicrobial activity of the mouthwash was evaluated by Agar well diffusion method against the tested microorganisms. The toxicity test was performed by using the MTT assay. The new formula has the potential to treat and prevent oral and throat infections. The newly developed Chlorhexidine mouthwash can be considered safe for oral usage.

Publisher

Trans Tech Publications, Ltd.

Subject

General Medicine

Reference12 articles.

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3. L.G. DePaola, A.E. Spolarich, Safety and Efficacy of Antimicrobial Mouthrinses in Clinical Practice, ADHA. 81 (2007) 117.

4. In Vitro Antifungal Properties of Mouthrinses Containing Antimicrobial Agents;Giuliana;Journal of Periodontology

5. Clinical Response to 2 Different Therapeutic Regimens to Treat Peri-Implant Mucositis;Porras;Journal of Periodontology

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