Abstract
The novel hemostatic film for the surgery of bone diseases was fabricated using TEMPO(2,2,6,6-tetramethylpiperidine-1-oxyl)-oxidized cellulose nanofibers (TOCNs), and phosphoryl oligosaccharides of calcium (POs-Ca) or sugar-containing hydroxyapatite (s-Ca10(PO4)6(OH)2; s-HAp). Three kinds of the hydrophilic and transparent films with the thicknesses of 10 to 20 μm were fabricated, i.e., TOCN, POs-Ca-added TOCN and s-HAp-added TOCN films. Among these films, the uptake amount of the simulated body fluid by s-HAp-added TOCN film was as high as 5,543%, which was expected to quickly stop bleeding of larger amount of blood for the hemostasis.
Publisher
Trans Tech Publications, Ltd.
Subject
Mechanical Engineering,Mechanics of Materials,General Materials Science
Reference17 articles.
1. C. Schonauer, E. Tessitore, G. Barbagallo, V. Albanese, A. Moraci, The use of local agents: bone wax, gelatin, collagen, oxidized cellulose, Eur. Spine J. 13 (Suppl. 1) (2004) S89–S96.
2. C. Hama, T. Umeda, Y. Musha, S. Koda, K. Itatani, Preparation of novel hemostatic material containing spherical porous hydroxyapatite/alginate granules, J. Ceram. Soc. Japan. 118 (2010) 446-450.
3. D. Yamashita, T. Umeda, Y. Musha, S. Koda, K. Itatani, Fabrication of Flexible Porous Whisker-Like Hydroxyapatite/Alginate Composite, J. Soc. Inorg. Mater. Japan.18 (2011)3-9.
4. E. Shima, T. Umeda, Y. Musha and K. Itatani, Properties of novel bone hemostat by random co-polymer of ethylene oxide and propylene oxide with sugar-containing hydroxyapatite, Adv. Mater. Lett. 7 (2016) 90-94.
5. T. Mimura, T. Umeda, Y. Musha, K. Itatani, Properties of novel bone hemostat prepared using hydroxyapatite, phosphoryl oligosaccharides of calcium and thermoplastic resin, J. Ceram. Soc. Japan. 121(2013) 68-73.
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