Chemical Constituents and Anti-Acetylcholinesterase Activities of Dolomiaea wardii

Author:

Li Chun Lei1,Sheng Jie1

Affiliation:

1. Lanzhou University of Technology

Abstract

The chemical composition of the ethyl acetate and n-butanol extracts of Dolomiaea wardii has been reported for the first time in the present study and eight compounds were isolated and identified as corymbolone(1), encelin(2), 8-oxoargentone(3), betulinic acid(4), lupeol(5), 4-hydroxyacetophenone(6), sweroside(7), Laganoside(8). anti-acetylcholinesterase activity of 1-8 showed that compound 6 have weak inhibitory activity with IC50 value of 1.43 mM.

Publisher

Trans Tech Publications, Ltd.

Subject

General Engineering

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