The Research of Laryngeal Reconstruction with Personalized Artificial Larynx Using Tissue Engineering

Abstract

It brings the pain to the patients whether in spirit or on physiology when laryngeal cartilage is injured. The paper reviewed the previous methods of improving the pronunciation for laryngeal cartilage injury and patients whose larynxes have been cut off, and compared the advantages and disadvantages of various methods. On the basis of the studies on the artificial auricle scaffold, artificial spinal cord scaffold in our center, this paper puts forward a larynx injury repair methods with a personalized tissue engineering artificial larynx, namely taking the advantages of biological manufacturing and tissue engineering related technology to prepare laryngeal cartilage scaffolds, and then the stem cells could be cultured into the scaffold in vitro. After more study and test, this bio-manufactured larynx scaffold could be expected as one of the ideal repair methods for the larynx injury.