Stability of Ultrathin Amorphous Calcium Phosphate Artificial Enamel Sheets under Simulated Intraoral Environment Condition

Abstract

Dental materials purely composed of calcium phosphate are ideal for the dental medicine. We have been developing ultrathin amorphous calcium phosphate (ACP) sheets for enamel repair. In this study, long term stability of the ultrathin ACP sheets applied on enamel surfaces which kept in a simulated intraoral condition for 21 days was evaluated. Surface morphologies of the ACP sheets were observed by optical images. A boundary condition between the ACP sheet and the enamel was evaluated by cross-sectional SEM image. A durability of the ACP sheet was evaluated by a brushing test conducted after 21 days incubation. As the result of these evaluations, it was confirmed that the ACP sheets were stable even after long-term incubation under the simulated intraoral environment condition.