Affiliation:
1. Pertamina University
2. Institut Teknologi Bandung
Abstract
The oxidation of quinine using hydrogen peroxide yielded quinine N-oxide as a major product. The reaction can be accelerated in the presence of palladium chloride (PdCl2) as catalyst. The trace products, however, were identified as the further oxidation products at quinoline moiety producing N-Oxide as a major product and the secondary alcohol at C-9 producing the ketone, furthermore the alkene translocation product. The trace products were successfully isolated and characterized by NMR protons and carbons. Purification of the product was performed by column chromatography.
Publisher
Trans Tech Publications, Ltd.
Subject
Mechanical Engineering,Mechanics of Materials,General Materials Science