Methods of Synthesis of Radiopharmaceuticals Based on Fatty Acids Marked with 99mTc and Perspectives of their Application

Abstract

The present paper gives an analytical review of methods for obtaining of radiopharmaceuticals that are based on 99mTc -labeled fatty acids and their use in cardiology. We make conclusion on the efficiency of application and investigation of 99mTcfatty acids radiopharmaceuticals that contain chelate groups EDTA or DTPA. In this study, quantum-chemical modeling of one of such conjugates is conducted and its bioavailability is confirmed.