Cell Growth Morphology on Nano-Structured Surface Based on Wetting

Abstract

This paper studied the growth morphology of the cells on the nanostructured surfaces of the bio-electrodes implanted in human patients. A transition model of the cells on those surfaces, which is the W model or C-B model, was deduced according to the effect of the microstructures on the wetting characteristics and the solid-liquid contact angle models of the microstructured surface. According to the contact angle formula of the model of the droplet on the solid surface, the formula was derived to describe the morphology of the ells on the nanostructured surface. The results of the experiments showed the impact of nanostructured to the morphology of the cells. The changes of the cell morphology on the smooth surface and the nanostructured surface showed that the cell morphology was affected by the nanostructures of solid surface, and the growth shape of cell was different when the sizes were different.