Tissue Distribution of Dechlorane Plus in Mugil Soiuy (Liza haematochella) from Liaodong Bay, China

Abstract

Tissue distribution is the foundation for estimating the toxicokinetics and potential risk of contaminants in organisms. Towards a better understanding of the biological effects mediated by the widely used pesticide Dechlorane plus (DP) in fish, the concentrations and isomer compositions of DP were examined in various tissues of Mugil soiuy (Liza haematochella), including the muscle, kidney, liver, gill, intestines, brain and eyes. The mechanisms of DP bioaccumulation were also investigated through correlating the concentrations of DP in different tissues with the lipid content of the tissues and thebody weight. The results show that DP is subject to biotransformation in Mugil soiuy. The highest concentration of T-DP was detected in the kidney and liver, followed by intestines, gill and muscle. Mechanisms of tissue were important determinants of DP levels, and followed by tissue lipid content. The values of fanti in analyzed tissues were easier enriched anti- than syn-DP.