SPECT with <sup>99m</sup>Tc-HMPAO and Cognitive Function in Patients with Arterial Hypertension: Impact of Antihypertensive Therapy-Reference-Cited by-同舟云学术

SPECT with ^99mTc-HMPAO and Cognitive Function in Patients with Arterial Hypertension: Impact of Antihypertensive Therapy

Published:2015-01 Issue: Volume:1084 Page:479-482
ISSN:1662-8985
Container-title:Advanced Materials Research
language:
Short-container-title:AMR

Author:

Efimova Irina Yu.¹,Efimova Nataliya Yu.¹,Triss Sergey V.¹,Zyablova Nataliya N.²

Affiliation:

1. Research Institute for Cardiology

2. Tomsk Polytechnic University

Abstract

The article is devoted to using brain SPECT with 99mTc-HMPAO for assessment of influence of antihypertensive therapy on the cerebral perfusion and cognitive function in arterial hypertension patients. By means of it is established that antihypertensive therapy has positive impact on brain perfusion within 6 months. In 24 weeks of hypotensive therapy there is an improvement of cognitive function: attention, psychomotor speed and thinking.

Publisher

Trans Tech Publications, Ltd.

Subject

General Engineering

Link

https://www.scientific.net/AMR.1084.479.pdf

Reference15 articles.

1. W.H. Birkenhäger, F. Forette, M. -L. Seux, J.G. Wang, J.A. Staessen, Blood pressure, cognitive functions, and prevention of dementias in older patients with hypertension, Arch. Intern. Med. 161 (2001) 152-156.

2. L. Kilander, H. Nyman, M. Boberg, L. Hansson, H. Lithell, Hypertension is related to cognitive impairment: a 20-year follow-up of 999 men, Hypertension. 31 (1998) 780–786.

3. L. Hansson, A. Himmelmann, T. Hedner, Hypertension of dementia: can antihypertensive treatment preserve cognitive function? Blood Pressure. 8(4) (1999) 196-197.

4. G. Goldstein, B.J. Materson, W.C. Cushman, D.J. Reda, E.D. Freis, E.A. Ramirez, F.N. Talmers, T.J. White, S. Nunn, R.H. Chapman, Treatment of hypertension in the elderly: II. Cognitive and behavioral function. Results of a Department of Veterans Affairs Cooperative Study, Hypertension. 15 (1990).

5. N.A. Lassen, A.R. Andersen, L. Fribrg, O.B. Paulson, The Retention of [99m-Tc]-d, l, -HMPAO in the Human Brain after Intracarotid Bolus injection: A Kinetic Analisis, J. Cerebral Blood Flow & Metab. 8 (1988) 13–22.