Affiliation:
1. M. Aikimbayev's Kasakh Scientific Center for Quarantine and Zoonotic Diseases
2. New York University
Abstract
The purpose of this study was to determine the microbiologic effect silver (Ag) when incorporated in amorphous calcium phosphate (ACP) prepared from solutions containing calcium, phosphate and pyrophosphate ions. The preparations were obtained from solutions with phosphate/pyrophosphate ratio, P/P2 = 7/3, and characterized as ACP using X-ray diffraction, infrared spectroscopy, nuclear magnetic resonance and differential thermal analysis. The microbes tested were cultures of E. Coli, St. aureus, Ps aerogunosa, C. diphteroides and C. albicans in media alone (control), with ACP without Ag and with ACP containing different Ag concentrations. Results demonstrated the following: (1) Ag in ACP inhibited the growth of microorganisms in all five cultures, with ACP containing 3-6% Ag giving the greatest antimicrobial effect; (2) sensitivity to the antimicrobial action of Ag differed among the bacteria.
Publisher
Trans Tech Publications, Ltd.
Subject
Mechanical Engineering,Mechanics of Materials,General Materials Science
Reference13 articles.
1. A Pommer, M.P. Hahn, G. Muhr: Am Acad Orthoped Surgeons 67th Annual Meeting, March 15- 19 (2000), abstract #72.
2. A.M. Mulligan, M. Wilson, J.C. Knowles. J. Biomed. Mater. Res. (2003) 67A: 401-412.
3. T. Gilchrist, D.M. Healy, C. Drake. Biomaterials (1991) 12: 76-78.
4. U. Klueh, V. Wagner, S. Kelly, A. Johnson, J.D. Bryers. J. Biomed. Mater. Res. (Appl. Biomat. ) (2000) 53: 621-631.
5. R.Z. LeGeros, W.P. Shirra, M.A. Miravite, J.P. LeGeros. CNRS No. 230. Physico-chimie et Crystallographie des Apatites d'Interet Biologique. Paris (1973), pp.105-115.
Cited by
8 articles.
订阅此论文施引文献
订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献