Relationship between the Structure and Electrical Conductivity of 12-Mer Single-Stranded Polyadenine Studied by Scanning Tunnelling Microscope-Reference-Cited by-同舟云学术

Relationship between the Structure and Electrical Conductivity of 12-Mer Single-Stranded Polyadenine Studied by Scanning Tunnelling Microscope

Published:2019-08 Issue: Volume:966 Page:119-125
ISSN:1662-9752
Container-title:Materials Science Forum
language:
Short-container-title:MSF

Author:

Rozak Harison¹,Zaharim Wan Nurfadhilah¹,Miyazaki Issei²,Ismail Nur Eliana¹,Abu Bakar Siti Nuramira¹,Kernain Daruliza¹,Samian Razip¹,Ichimura Koichi²,Mohamed-Ibrahim Mohamed Ismail¹,Sulaiman Shukri¹,Watanabe Isao¹

Affiliation:

1. Universiti Sains Malaysia

2. Hokkaido University

Abstract

Abstract: In order to investigate the structure and electrical conductivity of (DNA), Scanning Tunnelling Microscopy (STM) studies were carried out on a model of DNA which was composed of a 12-mer single-stranded polyadenine connected via sugar-phosphate backbone. The 12-mer single-stranded polyadenine molecules were found to be aligned in parallel to each other at a separation 25±7.5 Å. This alignment formed a one-dimensional chain structure, which indicated that the side-by-side coupling among the molecules was strong. The STM measurements with constant current mode and fixed bias voltage, demonstrate that, the electrical conductivity of DNA bases could be deduced by monitoring the size of the structure of 12-mer single-stranded polyadenine.

Publisher

Trans Tech Publications, Ltd.

Subject

Mechanical Engineering,Mechanics of Materials,Condensed Matter Physics,General Materials Science

Link

https://www.scientific.net/MSF.966.119.pdf

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