Strontium Modification of Biomaterial: The Effective Approach to Enhance the Bioactivity and Biocompatibility of Calcium Silicate

Abstract

Calcium silicate (CS), the recent developed biodegradable ceramic, shows potential in stimulating bone regeneration. However, the rapid degradation restricts its further application, that is, the cytotoxicity is highly suspicious. In this study, the attempt with the addition of strontium by partially replacing the site of calcium shows appropriate, not only enhancing the bioactivity of CS, but also promoting its biocompatibility. Thus, the modification of biomaterial by strontium seems to be an effective approach for biological application.