Affiliation:
1. National University of Defense Technology
2. Korea Institute of Science and Technology
Abstract
A promising series of biocidals based on imidazolium derivates were synthesized to develop new antiseptics and disinfectants. Biocidal Imidazoliums with hydrophobic alkyl substituents and hydrophilic substituents were prepared, and its antimicrobial activity (AM) was determined by Minimal inhibitory concentrations (MICs). It was found that the MIC value of the as-synthesized imidazole derivatives increase as the number of alkyl carbons increases up to 12 carbons,and its AM efficiency is relatively high.
Publisher
Trans Tech Publications, Ltd.
Reference9 articles.
1. Arias C A, Murray B E. N Engl J Med, 360: 439-43. (2009).
2. Li P, Poon YF, Li W, et al. Nat Mater, 10: 149-56. (2011).
3. Krutyakov Y A, Rukhlya E G, Artemov A V, Olenin A Y, Ivanov M N, Shelyakov O V. Nanotechnol Russia, 3: 756-62. (2008).
4. Anderson E, Long T E, Polymer, 51: 2447–2454. (2010).
5. Mukherjee A, Kumar S, Seth M, Bhaduri A P. Ind. J. Chem, 28B: 391. (1989).