Selective Detection of Dopamine in the Presence of Uric Acid Using Polymerized Phthalo Blue Film Modified Carbon Paste Electrode

Abstract

A convenient and useful method for the voltammetric determination of dopamine (DA) and uric acid (UA) based on poly (Phthalo blue) modified carbon paste electrode (PTBMCPE) is reported in this paper. The PTBMCPE exhibits excellent electro-catalytic activities for the oxidationreduction of DA and UA, as well as eliminating the interference. Factors influencing the detection processes are optimized and the kinetic parameters are calculated. The effects of pH, scan rate and concentration of dopamine on the peak current were investigated, and the results indicated that the peak current of dopamine is the highest in 0.2 M pH 7.0 Phosphate buffer solution (PBS) and the electrode reaction corresponds to a rate-controlled process. The proposed method possesses the distinct advantages of simple, appropriate for operation, good reproducibility and highly selective and sensitive.