Analyze the Relationship between TCM Prescription’ Dosage and Pharmacodynamic Effect Based on Uniform Design and Regression Method

Author:

Nie Bin1,Du Jian Qiang1,Yu Ri Yue2,Liu Yu Hui2,Xu Guo Liang2,Wang Yue Sheng3,Huang Li Ping2

Affiliation:

1. Jiang Xi University of Traditional Chinese Medicine

2. Jiangxi University of Traditional Chinese Medicine

3. National Pharmaceutical Engineering Centre for Solid Preparation in Chinese Herbal Medicine

Abstract

Traditional Chinese Medicine have the secret is dosage,the Traditional Chinese Medical clinical therapeutic effect key is prescription’ dosage. A majority of Chinese medicinal herbs are generally crude plants with fairly moderate nature and a relative wide-safety range of dosage,their doses may not be used so strictly as those of chemicals, but must within the limitation. The Traditional Chinese Medical dosage is yet affected by the follwing factors:properties of medicinal herbs,compatibility and formulation,the condition of illness,the patients’ physique and age,methods of decocting chinese medicinal herbs,methods of taking chinese medicinal,and etc. After exclude these factors, analyze the relationship between TCM prescription’ dosage and pharmacodynamic effect be of great signifiance.In this work, explore how to analyze the relationship between TCM prescription’ dosage and pharmacodynamic effect is a major goal. The paper put forward analyze the relationship between TCM prescription’ dosage and pharmacodynamic effect based on Uniform Design and regression method, It was proved to be feasible and effective after tested.

Publisher

Trans Tech Publications, Ltd.

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