Biomimetic Scaffolds Containing Chitosan and Hydroxyapatite for Bone Tissue Engineering

Abstract

In this work, genipin cross-linked chitosan (CS)/hydroxyapatite (HA) composite scaffolds were fabricated by a biomimetic method, followed by product freeze-drying. The fabricated composites were characterized by XRD, FT-IR, HRTEM, SEM and CLSM studies. Mechanical properties of the composite scaffolds have been significantly enhanced and can meet the demand of spongy bone. So the developed CS/HA scaffolds have advantageous and potential applications for bone tissue engineering.