Computational Fluid Dynamic Analysis of Customised Tibia Bone Scaffold

Abstract

The function of Tissue Engineering Bone Scaffold lies in Mechanical and Fluid dynamic behaviour to mimic the exact bone tissue. The fluid dynamic characteristic in a porous scaffold plays a vital role for cell viability and tissue regeneration. The Wall Shear Stress of fluid in a porous scaffold gives the cell proliferation. This paper presents, the patients CT scan data in DICOM format is exported into MIMICS software to convert the 2D images into 3D IGES data. The customised bone scaffolds with pore size of 0.6mm in diameter and distance between adjacent edges of pores from 0.6mm to 1mm are created in modeling software (SOLIDWORKS 2011) and porosities of five customised bone scaffolds are determined. The above customised bone scaffolds are analysed in CFD software (ANSYS CFX) for the fluid density 1000 kg/m3 and viscosity 8.2 ×10-4 kgm-1 s-1. The estimated Wall Shear Stress (WSS) at fluid velocities from 0.2mm/s to 1mm/s lies in the range of 9.54 x 10 -4 Pa to 38.3 x 10 -4 Pa.